Etanercept in the treatment of SAPHO syndrome: Which place?

Etanercept in the treatment of SAPHO syndrome: Which place?

Synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome (SAPHO) is a rare disease combining skin, bone, and joint manifestations. Its treatment remains a debated issue in the absence of a valid therapeutic strategy. The experience with tumor necrosis factor alpha (TNF alpha)-blocking agents is still small but encouraging. This therapy is reserved for refractory cases. The most commonly...

Etanercept in the treatment of refractory SAPHO syndrome.

OBJECTIVE To explore the application and efficacy of TNF-α inhibitors in the treatment of SAPHO syndrome. METHODS Two cases of refractory SAPHO syndrome were successfully treated with etanercept. And pain scores, laboratory parameters and functional index were used to judge the efficacies. Literature was also systemically reviewed. RESULTS Both patients achieved marked clinical remission. T...

the place of iranian public diplomacy in central asia

چکیده: نسبت به کارکرد و ماهیت دیپلماسی عمومی در جهان امروز نظریه های متعددی بیان گردیده و جایگاه آن در کنار نظریه های دیگر در محافل آکادمیک و دانشگاهی بررسی و تحلیل گردیده است. نظر به اهمیت دیپلماسی عمومی و جایگاه آن در سیاست خارجی ایران این نوشتار با تمرکز بر دیپلماسی عمومی در منطقه آسیای مرکزی تهیه و تنظیم شده است. این ضرورت از آنجا ناشی می شود که اولاً مفهوم دیپلماسی عمومی در سیاست خارجی ای...

Adalimumab treatment for SAPHO syndrome.

© 2010 The Authors. doi: 10.2340/00015555-0822 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 SAPHO syndrome is a rare condition of unknown pathogenesis originally described by Chamot et al. (1) in 1987. Onset usually occurs in young adults, with no differences between sexes and it is manifested by synovitis, acne, pustulosis, hyperostosis and osteitis. Of paramount impor...

SAPHO Syndrome